Midwest Express Clinic, 2601 W North Avenue
Open 8 am to 8 pm on weekdays and 8 am to 6 pm at weekends, with X-ray on site. It accepts most major insurance including Medicaid. Of every clinic we track in this area, this one has the strongest combination of rating and review volume — a high score that a large number of patients have contributed to, which is a more reliable signal than a higher score from a handful of reviews.
Booking is genuinely first-party, on the clinic’s own site rather than a third-party platform, and the clinic states that checking in online roughly halves the time you spend waiting.
We have not confirmed a direct phone number for this location or which languages are spoken there.
WellNow Urgent Care, 600 W North Avenue
This is the thinner of the two listings, and we want to be straight about that. We have not confirmed its opening hours, phone number, services, insurance or online check-in. Its Google listing is active with a small number of reviews, which suggests it is trading, but a small review count also means the rating rests on limited evidence. Call before you travel.
The hospital across the street
The detail most worth knowing in Melrose Park: Gottlieb Memorial Hospital sits at 701 West North Avenue, part of Loyola Medicine, with a 24-hour emergency department. That is directly across North Avenue from the WellNow clinic at number 600.
Two clinics and a hospital emergency department within a few hundred metres of each other is genuinely useful, but only if you pick the right door. The emergency department is open when both clinics are shut, and is the correct destination for anything serious. For a minor illness or injury during clinic hours, walking into the emergency department instead will usually cost several times more and take longer, because emergency departments see the sickest patients first. Our guide to urgent care versus the emergency room covers where the line falls, and chest pain is one symptom that should always take you across the road.
Comparing the two, and the alternatives
| Clinic | Google rating | Weekday hours | Book or call |
|---|---|---|---|
| AFC Urgent Care Cicero4769 W Cermak Rd, Ste. B, CiceroX-ray on siteLab on siteSe habla español | 4.9★★★★½175 reviews | 8:00 am – 8:00 pm | Check in online(708) 982-3898 |
| Midwest Express Clinic — Cicero3314 S Cicero Ave, Unit B, CiceroX-ray on siteLab on siteMedicaid | 4.8★★★★½1,205 reviews | 8:00 am – 8:00 pm | Check in online(708) 391-3030 |
| Midwest Express Clinic — Melrose Park2601 W North Ave, Melrose ParkX-ray on siteMedicaid | 4.8★★★★½950 reviews | 8:00 am – 8:00 pm | Check in online |
| Cermak Immediate Care — Cicero5741 W Cermak Rd, CiceroX-ray on siteLab on siteSe habla españolMedicaid | 4.7★★★★½3,379 reviews | 7:00 am – 11:59 pmLatest in Cicero | Check in online(708) 222-0100 |
| WellNow Urgent Care — Melrose Park600 W North Ave, Melrose Park | 4.5★★★★½44 reviews | — | No booking or phone on record |
Melrose Park is the furthest of the suburbs we cover from Cicero, so the Cicero clinics are a real drive rather than a quick hop. The exception is timing: nothing in Melrose Park is open past 8 pm, while Cermak Immediate Care in Cicero runs until 11:59 pm. See the full urgent care listing, or our Oak Park page for the nearest alternative in the other direction.
What these clinics treat
Midwest Express Clinic lists more than sixty services, including several our own guides cover: bronchitis and pneumonia, urinary tract infections, fractures and sports injuries, STD testing, allergies and paediatric urgent care. It also handles school, sports and camp physicals.
- Chest pain or pressure, or pain spreading to the arm or jaw
- Difficulty breathing, or breathlessness while sitting still
- Sudden weakness, facial drooping, or slurred speech
- Bleeding that will not stop under firm pressure
- A serious head injury, or any loss of consciousness
In Melrose Park the emergency department is unusually close: Gottlieb Memorial Hospital at 701 West North Avenue, open 24 hours, across the road from the WellNow clinic. See urgent care versus the emergency room for the full comparison.
Frequently asked questions
How many urgent care clinics are in Melrose Park, IL?
Two, both on North Avenue: Midwest Express Clinic at 2601 W North Avenue and WellNow Urgent Care at 600 W North Avenue.
Which urgent care in Melrose Park is better rated?
Midwest Express Clinic, and by a clear margin once review volume is taken into account — its rating rests on roughly twenty times as many reviews as the WellNow location’s.
Is there a hospital in Melrose Park?
Yes. Gottlieb Memorial Hospital at 701 West North Avenue, part of Loyola Medicine, operates a 24-hour emergency department. It is across North Avenue from the WellNow urgent care.
Where can I go in Melrose Park after 8 pm?
Both walk-in clinics close by 8 pm. After that the options are the 24-hour emergency department at Gottlieb Memorial Hospital, or Cermak Immediate Care in Cicero, open until 11:59 pm, which is much cheaper than an emergency room for a minor problem.
Does urgent care in Melrose Park take Medicaid?
Midwest Express Clinic states that it accepts Medicaid along with most major insurance. We have not confirmed coverage at the WellNow location.
Clinic details were checked on 2026-09-02 against each clinic’s own website and booking platform. Google ratings come from the Google Places API and are refreshed regularly. Where we could not confirm a detail we leave it blank rather than guess. Hours and insurance change without notice — call before you travel.